61-year-old Meg Ryan makes rare public appearance, sparks debate on internet – ‘what did she do to herself’

The Sleepless in Seattle Star, who made her on-screen debut in Rich and Famous (1981), displayed an incredibly smooth complexion, once again fueling rumors that she may have dabbled in plastic surgery, despite her previous denials.
Indeed, some shared less than flattering opinions over Meg’s new look online, reigniting a debate that the actress herself has weighed in on in the past.
“This is Meg Ryan,” one Twitter user commented. “Hopefully women will learn from this. Plastic Surgery is for Frankenstein.
“Meg Ryan spent thousands to make herself unrecognizable and hideous,” another added.

Another person wrote of the pictures, “what did she do to herself? These hollywood elites overdo the plastic surgery. Get a refund”
“Wtf has Meg Ryan done to her face?!” a third wrote.

n the past Ryan has insisted that she pays little attention to those offering negative opinions as to her appearance.
In a 2015 interview with Porter Magazine, she openly addressed the rumors regarding plastic surgery.
“I don’t pay a lot of attention, frankly,” she said at the time. “There’s a lot of hatred in the world today. It’s so easy to judge. Imagine being a hater, how stupid.”
Turning out for the aforementioned screening, held at the Alice Tully Hall in the Lincoln Center, New York, the actress seemed to be in good spirits as she posed for pictures with the likes of Billy Murray and Elvis Costello on Michael J. Fox’s big night.
Fox, who recently conceded that he didn’t think he would live to see 80 years old, is releasing a new documentary focusing on his life during the three decades since his diagnosis.

The Back to the Future star was first told he had Parkinson’s disease aged just 29. Despite initially endeavoring to hide his condition, he’s since become a leading figure in the fight for heightened awareness and research.
In a tear-jerking recent interview, Fox candidly reflected on his own mortality, saying that his ongoing battle with Parkinson’s was “getting tougher”

“I’m not gonna lie. It’s gettin’ hard, it’s gettin’ harder. It’s gettin’ tougher,” the retired actor said. “Every day it’s tougher. But, but, that’s, that’s the way it is. I mean, you know, who do I see about that?”
He added that he recently had spinal surgery after a tumor was found on his spine. While it was benign, it affected his ability to walk, and he was injured after a fall.
“[I] broke this arm, and I broke this arm, I broke this elbow. I broke my face. I broke my hand,” Fox said.

“You don’t die from Parkinson’s. You die with Parkinson’s. I’ve been thinking about the mortality of it. … I’m not gonna be 80. I’m not gonna be 80.”

Spe:rm Cells Carry Traces of Stress Experienced by the Father, New Study Shows

Can stress be passed down from one generation to the next? A groundbreaking study suggests that it can—at least in a way we never imagined before. Researchers have discovered that sperm cells can carry traces of stress experienced by the father, which may impact the health and stress response of future offspring.

This revelation challenges long-held beliefs about inheritance and genetics. Traditionally, we’ve assumed that only genetic sequences are passed down, but this study shows that environmental factors like stress can leave biological imprints on sperm. The implications? A father’s emotional and psychological well-being before conception could shape the mental and physical health of his children.

Let’s dive into what this means, how stress alters sperm cells, and what it could mean for future generations.

The Study: What Scientists Discovered

A team of researchers set out to explore how stress affects sperm and whether those changes could be passed to offspring. The study, conducted using animal models, found that sperm cells carry epigenetic markers influenced by stress levels prior to conception.

Epigenetics refers to changes in gene expression that do not alter the DNA sequence itself but can still be inherited. These changes act like biological “notes” added to genetic material, influencing how genes behave in offspring.

One of the most startling findings? The stress experienced by a father before conception may increase the likelihood of mental health disorders in his children. Anxiety, depression, and stress-related disorders could all be linked to epigenetic changes in sperm.

How Stress Affects Sperm Cells

The study uncovered specific biological mechanisms through which stress alters sperm. One of the primary processes involved is DNA methylation—a chemical modification that regulates gene activity.

Video : Sperm Memory Through Epigenetic : A Study Review

Here’s what happens:

  1. When a male experiences chronic stress, his body releases stress hormones like cortisol.
  2. These stress signals trigger epigenetic modifications in sperm, particularly in the form of DNA methylation.
  3. Once the sperm carries these changes, they can influence gene expression in the offspring, altering their stress response and overall health.

What does this mean in practical terms? Children of stressed fathers may have an increased sensitivity to stress, making them more prone to anxiety, depression, and other psychological conditions.

The Bigger Picture: Implications for Human Health

Although this study was conducted using animal models, the findings have far-reaching implications for human health. Traditionally, research on reproductive health has focused primarily on maternal factors, such as a mother’s diet, stress levels, and overall health during pregnancy.

This new research suggests we need to expand our focus to include paternal health. A father’s emotional and psychological well-being before conception could play a critical role in determining a child’s future health.

Some key takeaways:

  • Stress is not just a personal burden—it may have consequences for future generations.
  • Men’s health, both physical and mental, is an essential factor in reproductive success.
  • Healthcare approaches should address both maternal and paternal stress levels before conception.

Can These Changes Be Reversed?

One of the biggest questions this research raises is whether the effects of stress on sperm can be reversed. The good news? Some evidence suggests that lifestyle changes and stress reduction techniques may help restore healthier sperm function.

Potential ways to reduce stress-related epigenetic changes include:

  • Mindfulness and Meditation: Stress management techniques can help regulate cortisol levels and promote overall well-being.
  • Regular Exercise: Physical activity has been shown to reduce stress and improve reproductive health.
  • Healthy Diet: Nutrients like folate, zinc, and omega-3 fatty acids play a role in maintaining sperm quality.
  • Adequate Sleep: Poor sleep can increase stress hormones, which may contribute to epigenetic changes.
  • Therapy and Counseling: Addressing chronic stress through professional help can be beneficial for both mental and reproductive health.

While further research is needed, these lifestyle changes may provide a proactive way for men to optimize their reproductive health and reduce potential risks for their offspring.

Future Research: What’s Next?

While the current findings are groundbreaking, there are still many unanswered questions. Scientists are now investigating:

  • How long-lasting these epigenetic changes are: Could stress from years before conception still impact sperm quality?
  • Whether stress in different life stages (childhood vs. adulthood) affects sperm differently.
  • How interventions like diet and therapy might help reverse these epigenetic effects.

If scientists can pinpoint precise mechanisms and timelines, it could open the door to new reproductive health strategies, including stress-reduction programs for prospective fathers.

Final Thoughts: The Importance of Paternal Well-Being

This study marks a major shift in our understanding of inheritance and genetics. The idea that sperm carries traces of a father’s stress challenges old assumptions and highlights the importance of mental health in reproductive planning.

If you’re planning to have children in the future, this research is a wake-up call. Taking care of your mental and physical health isn’t just about you—it could impact your future children as well.

As science continues to reveal how our experiences shape future generations, one thing becomes clear: both parents’ well-being matters long before conception.

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