There are 14 main meridians that run through the body, 12 of which are aligned with the 24-hour clock. This means that there are two hours a day when a meridian – which runs through a certain part of your body – becomes the main one.

The meridians are related to body parts and processes, as well as emotions and experiences. In fact, the time you wake up can tell you which meridian is disturbed.
The time of night greatly determines what happens when you wake up. It is also important to consider how often you wake up at night. If you wake up every night between 3 and 5 a.m., it may mean that you are experiencing a spiritual awakening.
This is especially true if you never wake up during the night and there is no obvious reason (like going to the bathroom) why you woke up.
Spiritual significance of waking up at 1:00 a.m.
Physical: You may have circulation problems (especially your heart) or your gallbladder.
Mental: It means you have too much worry in your heart and mind. And these worries and resentments are now testing you.
Spiritual: You need energy. You are giving more than you are getting, and it is wearing you down. You may not be open to receiving, but you also may not know how to make yourself happy, so you rely on the idea of goals or the approval of others to do it for you.
Spiritual Significance of Waking up at 2 a.m.
Physical: You may be having digestive problems, either related to your small intestine or your liver. You may be eating or drinking too much or too little.
Mental: This is usually due to unresolved pockets of energy that you accumulated in early or middle childhood. When you were young, your inability to process what they meant made you either avoid or resist the circumstances in which they arose. Even today, it still has an impact on you.
Spiritual: You need to eliminate those old, limiting, inherited beliefs and ideas you have about yourself that you acquired before you were even aware of what was going on.
Spiritual meaning of waking up at 3 a.m.
Physical: You may have problems with your lungs. It may simply be an inability to breathe deeply and relax.
Mental: You need guidance and direction. Although you are beginning to have an awakening in your life, many things are still very new to you, so you are literally waking up in the spiritual “witching hour” (which is not necessarily a bad thing) to absorb more of the information you need.
Spiritual: Since 3am is the time when the veil between dimensions is at its lowest, it is possible that energies are trying to communicate with you (past loved ones, guides, etc.). It is also possible that, because you are becoming more sensitive to subtle energies, your body is waking up when there is more going on in the physical world. Stay awake and write down any messages you receive or ideas that pop into your head at this time.
Spiritual significance of waking up at 4 a.m.
Physical: You may have bladder or sweating problems. This is the time when your body temperature is lowest, so you may be too hot or too cold.
Mental: you may be too “hot or too cold” in your personal life, feeling both very fulfilled and sidelined by doubt. Know that this is part of the process, and will help you understand balance and duality.
Spiritual: You are in a time of ascension, upliftment and great change in your life. As you usher in the new, you must strive to accept letting go of the old.
Spiritual significance of waking up at 5am.
Physical: You may be having problems with your large intestine, or with your diet and nutrition.
Mental: You may not be convinced that you deserve the love of others or your own well-being. You are probably too caught up in your self-critical state of mind to really embrace all the amazing things you have built for yourself.
Spiritual: You are reaching a high point in your life where you are finally empowered, positive and thriving.
Waking up between 3 and 5 am can be a sign of a spiritual awakening.
Effects of smartphone restriction on cue-related neural activity
Smartphones have become an inseparable part of modern life, revolutionizing communication, work, and entertainment. However, excessive smartphone use (ESU) has been linked to various negative consequences, including addiction-like behaviors, impaired mental health, and diminished attention spans. Recent studies suggest that smartphone-related cues can trigger neural responses similar to those seen in substance addiction, reinforcing compulsive usage patterns. Understanding the effects of smartphone restriction on cue-related neural activity can provide valuable insights into developing interventions for individuals struggling with ESU.
The Role of Cue Reactivity in Smartphone Use

Cue reactivity (CR) refers to the brain’s response to stimuli associated with a habitual or addictive behavior. In the case of smartphone use, cues may include notification sounds, phone screens lighting up, or simply seeing a smartphone in one’s environment. These cues can activate reward-related brain regions, reinforcing the compulsive urge to check the device.
Research has shown that individuals with excessive smartphone use exhibit heightened neural responses to smartphone-related cues, similar to those observed in substance addiction. This heightened sensitivity may contribute to difficulty in controlling smartphone usage, leading to a cycle of compulsive checking and craving.
Investigating Neural Activity Changes Through Smartphone Restriction
To better understand how short-term smartphone restriction influences brain activity, researchers conducted a study using functional MRI (fMRI) to measure changes in cue-related neural responses over 72 hours of smartphone abstinence. The study involved 25 young adults who were regular smartphone users.
Video : What Happens To Your Brain When You Mindlessly Scroll?
Study Design and Methods
- Participants were instructed to refrain from using their smartphones for 72 hours.
- A cue-reactivity task was designed, where participants were exposed to images of smartphones (both active and inactive) as well as neutral objects.
- Functional MRI scans were conducted before and after the restriction period to analyze changes in brain activity.
- Psychometric assessments were used to measure craving, self-control, and emotional responses associated with smartphone use.
Key Findings: How the Brain Adapts to Smartphone Restriction
1. Reduced Activation in the Reward System
One of the most striking findings was a significant reduction in activity in the nucleus accumbens and anterior cingulate cortex after 72 hours of smartphone restriction. These brain regions are heavily involved in reward processing and habit formation.
- The nucleus accumbens is associated with motivation and reinforcement learning. High activation in this area suggests strong craving and compulsive behavior.
- The anterior cingulate cortex plays a role in decision-making and impulse control. Reduced activity here indicates that participants may have experienced less compulsion to check their smartphones.
These findings suggest that even a short break from smartphone use can lead to neuroplasticity, allowing the brain to become less reactive to smartphone-related cues.
2. Alterations in Dopamine and Serotonin-Linked Activity
Further analysis using neurotransmitter probability maps revealed that activity changes in the reward system were closely linked to dopamine and serotonin receptor probabilities.
- Dopamine is a key neurotransmitter in reward-seeking behavior and addiction.
- Serotonin is involved in mood regulation and impulse control.
The findings suggest that smartphone restriction may influence neurochemical processes that drive compulsive behaviors. This could explain why some people feel withdrawal-like symptoms, including restlessness and anxiety, when they suddenly stop using their phones.

3. Increased Engagement of the Parietal Cortex
Another notable result was the increased activity in the parietal cortex, a region associated with attentional control and sensory processing.
- This suggests that participants became more aware of their environment and less preoccupied with smartphone-related distractions.
- Heightened parietal cortex activity was correlated with reduced craving scores, indicating improved cognitive control over impulsive smartphone use.
This supports the idea that limiting smartphone use can enhance focus and attentional regulation, reducing dependency on digital devices.
4. Reduced Compulsive Checking Behavior
Behavioral assessments showed that participants experienced a significant decrease in the urge to check their smartphones over time. This aligns with the observed neural changes in reward sensitivity and impulse control.
Participants also reported improvements in:
- Sleep quality: Reduced exposure to blue light and nighttime scrolling led to better sleep patterns.
- Social interactions: Without constant phone distractions, participants engaged more with people around them.
- Mental well-being: Several individuals noted feeling less anxious and more present in their daily activities.
Implications for Smartphone Addiction and Digital Detox Strategies

The findings of this study have significant implications for individuals struggling with excessive smartphone use. While a complete break from smartphones may not be feasible for everyone, implementing digital detox strategies can help manage usage and mitigate negative effects.
1. Scheduled Smartphone Breaks
- Taking regular breaks from smartphone use, even for a few hours a day, can help reset neural responses to digital cues.
- Setting specific times for checking messages rather than responding to every notification can reduce compulsive checking.
2. Mindful Technology Use
- Practicing conscious smartphone use by turning off unnecessary notifications and using grayscale mode can help decrease reliance on digital stimuli.
- Engaging in non-digital hobbies, such as reading, exercise, or meditation, can strengthen attention control and reduce smartphone dependency.
3. Sleep Hygiene and Nighttime Restrictions
- Avoiding smartphone use one hour before bed can improve sleep quality by preventing blue light exposure.
- Using do not disturb or airplane mode at night can minimize the temptation to check notifications.
4. Awareness Campaigns and Education
- Schools, workplaces, and mental health professionals can promote awareness of the impact of excessive smartphone use on brain function.
- Implementing digital wellness programs can encourage balanced technology use.
Video : Cell Phones Affect Brain Activity

Conclusion: How Smartphone Restriction Reshapes the Brain
The study provides compelling evidence that even a short period of smartphone restriction can lead to measurable changes in brain activity. The observed reductions in reward-related neural responses, coupled with increased attentional control, suggest that limiting smartphone use can promote cognitive flexibility, impulse control, and overall mental well-being.
As smartphone addiction continues to be a growing concern, understanding the neurological basis of cue-reactivity and digital dependency is crucial. These findings highlight the importance of incorporating healthy technology habits to ensure that smartphones remain tools for convenience rather than sources of compulsive behavior.
By making small adjustments in smartphone usage, individuals can foster better focus, improved mental clarity, and greater overall life satisfaction. So, why not start with a 72-hour break and see how your brain adapts?
Leave a Reply