Actor Leslie Uggams has had an exciting career in both theater and film.
Even with a remarkable career spanning seven decades, the singer and actress from Harlem is best known for her role in the *Deadpool* series.
However, her marriage to White Australian Grahame Pratt in 1965 challenged expectations for interracial relationships, making her life story worthy of a movie.
In 1953, Leslie, a talented singer, recorded a song for MGM when she was just 10 years old. Her aunt, soprano Eloise Uggams, recommended that she attend the famous Julliard School of Music in New York and the Professional Children’s School of New York.
But her career didn’t stop after her musical success; in 1969, she hosted *The Leslie Uggams Show,* the first network variety show hosted by a Black person since *The Nat King Cole Show.*

However, Leslie got to know and fell in love with actor Grahame Pratt behind the scenes. During one of her famous tours in Australia, the pair reconnected in Sydney after first meeting as students at the Professional Children’s School in New York.
Leslie was aware of the challenges of dating a white man because she had dated one in her youth and her aunt had discouraged her from thinking about a future with him. Leslie shared with Ebony in 1967, “I remember the shock I felt once when I was dating a white boy.”
He sent me a color photo of himself. I showed it to my aunt. He was a young, attractive man with nice hair. I thought he was very good-looking. But my aunt lectured me after she saw the picture. “Well, I guess he’s alright,” she said, “but only on dates, huh, honey? When you’re ready to settle down, you’ll marry a nice [Black] fella, won’t you?”
Leslie said that after their lucky meeting, she kept visiting Grahame.
“At just 21 years old, it was surprising that I started to fall in love with him.”
It would be a full year before she saw him again after she left Australia.
Leslie was worried about how her family would react and what would happen if Grahame moved to the U.S. for her job, but despite her worries, they had fallen in love. When they had been engaged for five months, Grahame visited her in New York.
“I wanted to know if my family would truly accept Grahame and not just tolerate him, knowing their views on mixed marriages,” she said.
Leslie didn’t have to worry because Grahame was Australian.

“Many white Americans feel awkward about their situation, but he didn’t.” He got along well with my friends, so he easily fit in with them. And both the men and women liked him.
While living in New York, Leslie said she received hate mail because of their marriage, even though they didn’t face the same racial issues as many others in the country.
In an interview with PEOPLE, Leslie said about her marriage, “It wasn’t as difficult as I expected. I think it’s because Grahame wasn’t a white man in America.” Naturally, they did receive some negative mail.
Leslie shared, “I sometimes get anonymous letters about being married to a white man when I go on tour in the United States. I remember getting one, of all places, in Detroit.” It was addressed to “The Little Negro Entertainer.” Those letters were painful to read and often used that term.
Grahame took on the role of Leslie’s manager, and the couple had two daughters, Danielle in 1970 and Justice in 1976.
Leslie got the lead role in the miniseries Roots in 1977, a year after their second child was born. For that role, she was nominated for an Emmy for her character Kizzy.
Two years later, she played Lillian Rogers Parks in the miniseries Backstairs at the White House, earning another Emmy nomination for Best Actress.

In 1983, she won a Daytime Emmy Award for hosting the NBC game show Fantasy, and in 1996 she played Rose Keefer on All My Children.
Leslie has also made appearances on shows like Family Guy, I Spy, Hollywood Squares, The Muppet Show, The Love Boat, and Magnum P.I.
After fifty-five years of marriage and a granddaughter named Cassidy, Leslie and Grahame are still happily together.
“We have a lot of fun together, but it’s not always sunshine and roses,” Leslie said about their happy marriage. “We enjoy being together.”
Their love has stood the test of time and defied expectations. They support each other because they are loyal to one another and have always helped each other.
Scientists Discover the Reason Humans Lost Their Tails
One of the most remarkable changes in human evolution is the loss of our tails, a transformation that occurred around 25 million years ago. This pivotal shift not only altered the trajectory of our species but also marked a significant moment in the evolutionary history of primates. While scientists have long speculated on why humans lost their tails, the genetic cause has remained elusive—until now. A recent study published in Nature has finally uncovered the genetic factors responsible for this evolutionary change.

The Quest to Understand Tail Loss
The journey to unravel the mystery of human tail loss began in an unexpected way. Bo Xia, a graduate student at New York University, was inspired to investigate the origins of the human tailbone after injuring his own coccyx. This personal curiosity led Xia and his team to embark on a groundbreaking scientific investigation.
Through careful research, the team focused on the TBXT gene, which plays a crucial role in regulating tail length in various species. Their research revealed a unique genetic mutation within this gene, providing a major breakthrough in understanding human evolution.
The Role of Jumping Genes
A key aspect of this discovery lies in the role of Alu elements, often called “jumping genes.” These genetic elements, specific to primates, can move within the genome and cause significant changes. The researchers found that Alu elements inserted themselves into the TBXT gene, triggering a chain reaction that led to the loss of our tails.
This insertion activated a process known as alternative splicing, where RNA molecules are cut and restructured, which ultimately led to the deletion of a crucial exon. This change altered the structure and function of the resulting protein, leading to the tail loss seen in humans.
Validation Through Mice Studies
To confirm their findings, the researchers engineered laboratory mice with the same genetic mutations found in humans and apes. These genetically altered mice lost their tails, providing compelling evidence that the identified mutation plays a crucial role in the absence of tails in humans and other primates.
However, the study also uncovered a downside to tail loss: an increased risk of neural tube defects, such as spina bifida. This finding highlights the complex balance between evolutionary benefits and potential genetic trade-offs.
The Broader Implications
This discovery has profound implications not just for understanding human evolution, but also for human anatomy and health. The loss of our tails was not a random event but a genetic adaptation with lasting consequences. It illustrates the complex relationship between genetic changes and the way they shape our physiology over time.
As we continue to study our evolutionary past, these findings remind us of the intricate process of natural selection and genetic innovation that has shaped humanity. This breakthrough also underscores the power of scientific inquiry in uncovering the mysteries of our origins, offering insight into the past that can help us understand our future.
The identification of the genetic reasons behind tail loss is a testament to the persistence of scientific exploration and the ongoing quest for knowledge about our evolutionary journey.
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